Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770536 | 0.88 | BACE1 (0.62) | BACE1KMT2AL3MBTL1TSHRMAPK1 | |
| SCHEMBL9770438 | 0.87 | TSHR (0.59) | BACE1L3MBTL1MAPTTSHRMAPK1 | |
| SCHEMBL9770148 | 0.84 | BACE1 (0.58) | BACE1KMT2AL3MBTL1HTTTSHR | |
| SCHEMBL9770455 | 0.84 | BACE1 (0.58) | BACE1ADRB2ADRB1KMT2AL3MBTL1 | |
| SCHEMBL9770403 | 0.84 | BACE1 (0.58) | BACE1KMT2AL3MBTL1MEN1MAPT | |
| SCHEMBL9770562 | 0.83 | BACE1 (0.67) | BACE1ADRB2ADRB1KMT2AMEN1 | |
| SCHEMBL9480490 | 0.83 | BACE1 (0.80) | BACE1ADRB2ADRB1KMT2AL3MBTL1 | |
| SCHEMBL9770407 | 0.83 | BACE1 (0.52) | BACE1ADRB2ADRB1KMT2AL3MBTL1 | |
| SCHEMBL9770389 | 0.83 | BACE1 (0.64) | BACE1KMT2AGAA | |
| SCHEMBL9770232 | 0.83 | BACE1 (0.64) | BACE1KMT2AL3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |