SCHEMBL9770457

SCHEMBL9770457

O=c1cc(Cc2ccccc2)n(Cc2ccccc2)n1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 7/20 0.45
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
NAPRT Q6XQN6 1/20 0.40
F2 P00734 1/20 0.39
PLG P00747 1/20 0.39
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
CTRC Q99895 1/20 0.39
EHMT2 Q96KQ7 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP3A4 P08684 1/20 0.37
HSD11B1 P28845 1/20 0.37
GSK3A P49840 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9770452 0.79 NAPRT (0.57) IDH1ALDH1A1KDM4ELMNANAPRT
SCHEMBL5421935 0.79 NAPRT (0.57) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL5482874 0.72 NAPRT (0.49) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL14583502 0.70 KDM4E (0.46) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL14404406 0.70 MEN1 (0.46) IDH1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL9867787 0.68 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL9359607 0.68 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL11271717 0.67 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL2168584 0.65 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL3529533 0.65 NAPRT (0.51) ALDH1A1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
US-4918045-A SUPPORTS, MICROCAPSULES CONTAINING COLORLESS ELECTRON-DONATING COLOR FORMER AND SOLVENT, AND ELECTRON-ACCEPTING DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
US-4888321-A SUBBING AND RECORDING LAYERS EACH CONTAINING HEAT FUSIBLE MATERIAL WITH DEFINED MELTING POINT FUJI PHOTO FILM CO., LTD. (JP) 1989-12-19 US disclosed
US-4876233-A NICKEL COMPOUNDS; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1989-10-24 US disclosed
US-4871713-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US disclosed
US-4870048-A COLORFAST IMAGE, LIGHT RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1989-09-26 US disclosed
US-4839332-A AMINO-SUBSTITUTED FLUORENE AND ACID; DISCOLORATION INHIBITON, CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1989-06-13 US disclosed
US-4833118-A COLOR DEVELOPERS, SUBBING LAYERS, AROMATIC ESTERS OR CARBONATES FUJI PHOTO FILM CO., LTD. (JP) 1989-05-23 US disclosed
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed