SCHEMBL9359607

SCHEMBL9359607

O=c1[nH]c(=O)n(-c2ccccc2)n1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 4/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
DAO P14920 1/20 0.45
HPGD P15428 4/20 0.42
CYP3A4 P08684 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
F2 P00734 1/20 0.42
PLG P00747 1/20 0.42
ELANE P08246 1/20 0.42
CTSG P08311 1/20 0.42
CMA1 P23946 1/20 0.42
CTRC Q99895 1/20 0.42
GSK3A P49840 2/20 0.40
GSK3B P49841 2/20 0.40
MGLL Q99685 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9867787 1.00 ALDH1A1 (0.47) ALDH1A1KDM4EKMT2AMEN1LMNA
SCHEMBL11271717 0.98 ALDH1A1 (0.46) ALDH1A1KDM4EKMT2AMEN1LMNA
SCHEMBL8128786 0.80 GSK3A (0.54) ALDH1A1KMT2AMEN1SMN1; SMN2GSK3A
Potassium SCHEMBL11261679 0.78 GSK3A (0.52) ALDH1A1KMT2AMEN1LMNASMN1; SMN2
SCHEMBL9364231 0.75 SMN1; SMN2 (0.43) ALDH1A1KDM4EKMT2AMEN1HPGD
SCHEMBL14404406 0.70 MEN1 (0.46) ALDH1A1KDM4EKMT2AMEN1LMNA
SCHEMBL14583502 0.70 KDM4E (0.46) ALDH1A1KDM4EKMT2AMEN1LMNA
SCHEMBL14950255 0.70 MAPK8 (0.56) ALDH1A1KDM4EKMT2AMEN1DAO
SCHEMBL11430292 0.69 NAPRT (0.48) ALDH1A1KDM4EKMT2ALMNAMAPT
SCHEMBL5421935 0.69 NAPRT (0.57) ALDH1A1KDM4EKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0267491-B1 Silver halide light-sensitive photographic material containing a novel yellow coupler KONISHIROKU PHOTO IND (JP) 1994-03-09 EP disclosed
US-5066576-A Yellow coupler with good photostability FUJI PHOTO FILM CO., LTD. (JP) 1991-11-19 US disclosed
US-4992360-A Silver halide light-sensitive photographic material containing a novel yellow coupler KONICA CORPORATION (JP) 1991-02-12 US disclosed
EP-0267491-A2 Silver halide light-sensitive photographic material containing a novel yellow coupler KONICA CORPORATION (JP) 1988-05-18 EP disclosed
US-4362878-A DEVELOPMENT INHIBITOR RELEASE AGENTS CIBA-GEIGY AG (CH) 1982-12-07 US disclosed
US-4289847-A 2-EQUIVALENT YELLOW COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-09-15 US disclosed
US-4259437-A EXCELLENT INTRA-IMAGE AND INTER-IMAGE EFFECTS OF EXCELLENT SPEED CIBA-GEIGY AG (CH) 1981-03-31 US disclosed