Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770487 | 0.91 | CASR (0.40) | KMT2AMEN1HTTUSP2CYP1A2 | |
| SCHEMBL9770447 | 0.85 | BACE1 (0.57) | KMT2AMEN1HTTUSP2CYP1A2 | |
| SCHEMBL9770500 | 0.85 | KMT2A (0.45) | KMT2AMEN1CYP1A2CYP2C19GAA | |
| SCHEMBL9770448 | 0.81 | BACE1 (0.59) | KMT2ARAB9ABACE1MAPTNPC1 | |
| SCHEMBL9770497 | 0.81 | NPC1 (0.57) | KMT2AMEN1CYP1A2RAB9ABACE1 | |
| SCHEMBL9770371 | 0.80 | BACE1 (0.45) | KMT2ARAB9ABACE1MAPK1NPC1 | |
| SCHEMBL9770474 | 0.79 | BACE1 (0.62) | KMT2ARAB9ABACE1SMN1; SMN2NPC1 | |
| SCHEMBL9770575 | 0.79 | KMT2A (0.48) | KMT2AMEN1CYP1A2RAB9ABACE1 | |
| SCHEMBL9770521 | 0.78 | BACE1 (0.52) | KMT2AMEN1HTTUSP2CYP1A2 | |
| SCHEMBL9770535 | 0.77 | BACE1 (0.57) | KMT2AMEN1HTTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |