Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770448 | 0.91 | BACE1 (0.59) | BACE1NPC1RAB9APPARDKMT2A | |
| SCHEMBL9770331 | 0.91 | BACE1 (0.52) | BACE1NPC1RAB9APPARDKMT2A | |
| SCHEMBL9770507 | 0.91 | BACE1 (0.52) | BACE1NPC1RAB9APTGS1SLC6A2 | |
| SCHEMBL9770497 | 0.91 | NPC1 (0.57) | BACE1NPC1RAB9APPARDKMT2A | |
| SCHEMBL9770535 | 0.89 | BACE1 (0.57) | BACE1NPC1RAB9APPARDKMT2A | |
| SCHEMBL9770472 | 0.86 | MAPT (0.58) | BACE1PPARD | |
| SCHEMBL9770536 | 0.86 | BACE1 (0.62) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9770581 | 0.85 | ALDH1A1 (0.48) | BACE1KMT2ASMN1; SMN2 | |
| SCHEMBL9770370 | 0.85 | BACE1 (0.53) | BACE1PPARDKMT2ASMN1; SMN2 | |
| SCHEMBL9770570 | 0.85 | BACE1 (0.76) | BACE1NPC1RAB9APTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |