Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770448 | 0.92 | BACE1 (0.59) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770474 | 0.89 | BACE1 (0.62) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770331 | 0.86 | BACE1 (0.52) | BACE1PKMKMT2ANPC1RAB9A | |
| SCHEMBL9770497 | 0.86 | NPC1 (0.57) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770507 | 0.86 | BACE1 (0.52) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770370 | 0.85 | BACE1 (0.53) | BACE1KMT2AMEN1LMNAPPARD | |
| SCHEMBL9770321 | 0.85 | BACE1 (0.76) | BACE1PKMKMT2AKDM1AMAOA | |
| SCHEMBL9770472 | 0.81 | MAPT (0.58) | BACE1MAOAMAOBLMNAPPARD | |
| SCHEMBL9770581 | 0.81 | ALDH1A1 (0.48) | BACE1PKMKMT2AMEN1LMNA | |
| SCHEMBL9770514 | 0.80 | CA1 (0.45) | BACE1KMT2AMAOAMAOBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |