Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978328 | 0.85 | MCL1 (0.65) | MCL1TSHRALOX15KMT2AKDM4E | |
| SCHEMBL9559835 | 0.80 | MCL1 (0.46) | MCL1TSHRHPGDKMT2AKDM4E | |
| SCHEMBL11095697 | 0.80 | KDM4E (0.58) | MCL1TSHRHPGDALOX15KDM4E | |
| SCHEMBL11162400 | 0.80 | HSD17B10 (0.47) | MCL1TSHRHPGDALOX15KMT2A | |
| SCHEMBL21843804 | 0.79 | MAP2K2 (0.49) | MCL1TSHRHPGDALOX15MAP2K2 | |
| Hydrochloric Acid SCHEMBL11278666 | 0.79 | KDM4E (0.57) | MCL1TSHRHPGDALOX15KDM4E | |
| SCHEMBL4952867 | 0.78 | TSHR (0.50) | MCL1IKBKBTSHRHPGDALOX15 | |
| SCHEMBL30826508 | 0.77 | MCL1 (0.55) | MCL1TSHRHPGDALOX15MAP2K2 | |
| SCHEMBL9102881 | 0.77 | HPGD (0.48) | MCL1TSHRHPGDALOX15MAP2K2 | |
| SCHEMBL21947304 | 0.76 | DGAT1 (0.55) | MCL1TSHRHPGDALOX15MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |