Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.97 |
| ▸ | PKM | P14618 | 2/20 | 0.97 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.65 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoylpas SCHEMBL563122 | 0.98 | KMT2A (1.00) | KMT2APKMMAPTKDM4EMAPK1 | |
| Benzoylpas SCHEMBL29353120 | 0.97 | KMT2A (0.97) | KMT2APKMMAPTKDM4EMAPK1 | |
| Benzoylpas SCHEMBL8748163 | 0.97 | KMT2A (0.97) | KMT2APKMMAPTKDM4EMAPK1 | |
| SCHEMBL27296254 | 0.92 | KMT2A (0.87) | KMT2APKMMAPTKDM4EMAPK1 | |
| SCHEMBL30772317 | 0.92 | KMT2A (0.87) | KMT2APKMMAPTKDM4EMAPK1 | |
| SCHEMBL3296397 | 0.89 | KMT2A (0.83) | KMT2APKMMAPTKDM4EMAPK1 | |
| SCHEMBL13187383 | 0.86 | KMT2A (0.78) | KMT2APKMMAPTKDM4EMAPK1 | |
| SCHEMBL1129948 | 0.85 | KMT2A (0.77) | KMT2APKMMAPTKDM4EMAPK1 | |
| SCHEMBL11593167 | 0.85 | KMT2A (0.76) | KMT2APKMMAPTKDM4EKCNK3 | |
| Benzoylpas SCHEMBL1649155 | 0.84 | KMT2A (0.75) | KMT2APKMMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046270-B1 | NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | INTERx RESEARCH CORPORATION (US) | 1986-05-21 | — | — | EP | claimed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| US-5001115-A | Prodrugs of biologically active hydroxyaromatic compounds | UNIVERSITY OF FLORIDA (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | disclosed |