Sugi Predict

Sugi Predict / Compounds / Benzoylpas

Benzoylpas

Benzoylpas

SCHEMBL563122

O=C(Nc1ccc(C(=O)O)c(O)c1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 1.00
▸ PKM P14618 2/20 1.00
▸ MAPT P10636 2/20 0.69
▸ KDM4E B2RXH2 2/20 0.69
▸ MAPK1 P28482 1/20 0.69
▸ SIRT6 Q8N6T7 1/20 0.67
▸ KCNK3 O14649 1/20 0.61
▸ KCNK9 Q9NPC2 1/20 0.61
▸ ALOX15 P16050 1/20 0.57
▸ NPC1 O15118 4/20 0.57
▸ RAB9A P51151 4/20 0.57
▸ PTPN1 P18031 1/20 0.56
▸ MEN1 O00255 3/20 0.56
▸ GRIK1 P39086 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ SIRT1 Q96EB6 2/20 0.54
▸ POLB P06746 1/20 0.54
▸ FFAR1 O14842 1/20 0.54
▸ ACE2 Q9BYF1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoylpas SCHEMBL9770542 0.98 KMT2A (0.97) KMT2APKMMAPTKDM4EMAPK1
Benzoylpas SCHEMBL8748163 0.98 KMT2A (0.97) KMT2APKMMAPTKDM4EMAPK1
Benzoylpas SCHEMBL29353120 0.98 KMT2A (0.97) KMT2APKMMAPTKDM4EMAPK1
SCHEMBL27296254 0.93 KMT2A (0.87) KMT2APKMMAPTKDM4EMAPK1
SCHEMBL30772317 0.93 KMT2A (0.87) KMT2APKMMAPTKDM4EMAPK1
SCHEMBL3296397 0.91 KMT2A (0.83) KMT2APKMMAPTKDM4EMAPK1
SCHEMBL13187383 0.88 KMT2A (0.78) KMT2APKMMAPTKDM4EMAPK1
SCHEMBL1129948 0.87 KMT2A (0.77) KMT2APKMMAPTKDM4EMAPK1
SCHEMBL11593167 0.86 KMT2A (0.76) KMT2APKMMAPTKDM4EKCNK3
Benzoylpas SCHEMBL1649155 0.86 KMT2A (0.75) KMT2APKMMAPTKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115915796-A Multifunctional Lewis base molecule modified high-stability perovskite solar cell 河北工业大学 2023-04-04 — — CN claimed
US-11136342-B2 Carbonate prodrugs and methods of using the same ACORDA THERAPEUTICS, INC. (US) 2021-10-05 — — US claimed
CN-108774426-B High-performance surface mounting ink and preparation method thereof 南雄市科鼎化工有限公司 2021-08-24 — — CN claimed
CN-109021502-B Outer layer hole plugging resin and preparation method thereof 南雄市科鼎化工有限公司 2020-07-31 — — CN claimed
US-20200157126-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME ACORDA THERAPEUTICS, INC. 2020-05-21 — — US claimed
US-10377779-B2 Carbonate prodrugs and methods of using the same ACORDA THERAPEUTICS, INC. (US) 2019-08-13 — — US claimed
US-20190008848-A1 IDENTIFICATION OF ADDITIONAL ANTI-PERSISTER ACTIVITY AGAINST BORRELIA BURGDORFERI FROM AN FDA DRUG LIBRARY THE JOHNS HOPKINS UNIVERSITY 2019-01-10 — — US claimed
US-20180086778-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME NEUROGESX, INC. 2018-03-29 — — US claimed
WO-2017034984-A1 IDENTIFICATION OF ADDITIONAL ANTI-PERSISTER ACTIVITY AGAINST BORRELIA BURGDORFERI FROM AN FDA DRUG LIBRARY THE JOHNS HOPKINS UNIVERSITY (US) 2017-03-02 — — WO claimed
US-20150328323-A1 Nitric Oxide Releasing Produgs of Therapeutic Agents SATYAM APPARAO (IN) 2015-11-19 — — US claimed
EP-1718286-A2 NITROSATED AND/OR NITROSYLATED COMPOUNDS, COMPOSITIONS AND METHODS OF USE Nitromed, Inc. (US) 2006-11-08 — — EP claimed
WO-2005070006-A2 NITROSATED AND/OR NITROSYLATED COMPOUNDS, COMPOSITIONS AND METHODS OF USE NITROMED, INC. (US) 2005-08-04 — — WO claimed
JP-2003515526-A — — 2003-05-07 — — JP claimed
EP-1252133-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-10-30 — — EP claimed
EP-1192129-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-04-03 — — EP claimed
WO-2001012584-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2001-02-22 — — WO claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 — — WO claimed
WO-1998022114-A1 A METHOD FOR PROMOTING TISSUE REPAIR DUMEX-ALPHARMA A/S (DK) 1998-05-28 — — WO claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 — — EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200157126-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME CA6, CA7, CA4 KMT2A 2173/4885PKM 1313/4885MAPT 3060/4885
US-11136342-B2 Carbonate prodrugs and methods of using the same CA6, CA7, CA4 KMT2A 2173/4885PKM 1313/4885MAPT 3060/4885
US-20150328323-A1 Nitric Oxide Releasing Produgs of Therapeutic Agents NOS2, NOS1, PTGIS KMT2A 4534/4885PKM 1797/4885MAPT 3547/4885
US-10377779-B2 Carbonate prodrugs and methods of using the same CA6, CA7, CA4 KMT2A 2173/4885PKM 1313/4885MAPT 3060/4885
US-20180086778-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME CA6, CA7, CA4 KMT2A 2173/4885PKM 1313/4885MAPT 3060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.