Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544758 | 0.86 | PTGDR2 (0.52) | ALDH1A1MAPTLMNASMN1; SMN2PTGDR2 | |
| SCHEMBL5396606 | 0.84 | KMT2A (0.53) | ALDH1A1MAPTLMNASMN1; SMN2PTGDR2 | |
| SCHEMBL6928011 | 0.84 | KMT2A (0.53) | ALDH1A1MAPTLMNASMN1; SMN2PTGDR2 | |
| SCHEMBL1549394 | 0.84 | PTGS2 (0.54) | ALDH1A1MAPTLMNASMN1; SMN2PTGDR2 | |
| SCHEMBL17371402 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNASMN1; SMN2PTGDR2 | |
| SCHEMBL9722709 | 0.84 | MAPT (0.63) | ALDH1A1MAPTLMNASMN1; SMN2PTGDR2 | |
| SCHEMBL9770348 | 0.84 | KMT2A (0.53) | ALDH1A1MAPTLMNASMN1; SMN2PTGDR2 | |
| SCHEMBL8865199 | 0.83 | MAPT (0.55) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL9770414 | 0.82 | PTGDR2 (0.49) | ALDH1A1MAPTLMNASMN1; SMN2PTGDR2 | |
| SCHEMBL22381241 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021559-A | Water-soluble azo compounds containing a fiber-reactive group of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-5010180-A | Printing, dyeing | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |