Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45275 | 0.76 | MEN1 (0.30) | — | |
| SCHEMBL1598735 | 0.71 | — | — | |
| SCHEMBL30605 | 0.71 | TSHR (0.38) | ALDH1A1 | |
| SCHEMBL423317 | 0.71 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL11873748 | 0.70 | — | — | |
| SCHEMBL9570202 | 0.69 | LPAR2 (0.32) | ALDH1A1 | |
| SCHEMBL3507987 | 0.69 | CYP3A4 (0.32) | ALDH1A1 | |
| SCHEMBL3203191 | 0.67 | TP53 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL15847030 | 0.67 | LPAR3 (0.50) | TDP1 | |
| SCHEMBL9065637 | 0.67 | LPAR2 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987128-A | ANTIALDOSTERONES, NATRIURETICS | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4701449-A | Novel 10-substituted steroids and their use in the induction of aldosterone antagonistic activity | ROUSSEL UCLAF (FR) | 1987-10-20 | — | — | US | disclosed |