Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770522 | 0.85 | HDAC1 (0.44) | HDAC1HDAC6NPC1RAB9AALDH1A1 | |
| SCHEMBL9770662 | 0.84 | MCL1 (0.49) | HDAC1HDAC6KMT2AALDH1A1MEN1 | |
| SCHEMBL2688968 | 0.78 | HDAC1 (0.45) | HDAC1HDAC6CXCR4 | |
| SCHEMBL29640806 | 0.78 | HDAC1 (0.45) | HDAC1HDAC6CXCR4 | |
| SCHEMBL2597816 | 0.77 | HDAC1 (0.46) | HDAC1HDAC6ALDH1A1CXCR4 | |
| SCHEMBL27766407 | 0.76 | HDAC1 (0.44) | HDAC1HDAC6CXCR4 | |
| SCHEMBL2305432 | 0.76 | HDAC1 (0.45) | HDAC1HDAC6CXCR4 | |
| SCHEMBL30558705 | 0.75 | HDAC1 (0.46) | HDAC1HDAC6KMT2AALDH1A1MEN1 | |
| SCHEMBL27951689 | 0.75 | HDAC1 (0.46) | HDAC1HDAC6CXCR4 | |
| SCHEMBL3312236 | 0.75 | HDAC1 (0.46) | HDAC1HDAC6KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001131-A | Pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1991-03-19 | — | — | US | disclosed |