SCHEMBL977073

SCHEMBL977073

CCC1(CC)CC2(CC(C)(C)N1OC(C)c1ccc(OCC3CO3)cc1)OCC(COC(=O)c1ccc(C(=O)OCC3COC4(CC(C)(C)N(OC(C)c5ccc(OCC6CO6)cc5)C(CC)(CC)C4)O3)cc1)O2

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12922163 0.96 GRM2 (0.35) GRM2NPC1
SCHEMBL976763 0.94 GRM2 (0.33) GRM2NPC1RAB9AHTR7
SCHEMBL977051 0.93 TP53 (0.31) GRM2
SCHEMBL12922169 0.90 GRM2 (0.37) GRM2NPC1
SCHEMBL6864533 0.89 MGLL (0.34)
SCHEMBL5559670 0.89 POLB (0.36) NPC1HTR7
SCHEMBL976037 0.89 TP53 (0.34) GRM2
SCHEMBL976788 0.88 TP53 (0.33) GRM2
SCHEMBL977288 0.88 TP53 (0.33) GRM2
SCHEMBL975728 0.87 NLRP3 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 US claimed
EP-1341763-B1 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION CIBA SC HOLDING AG (CH) 2004-06-16 EP claimed
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization CIBA SPECIALTY CHEMICALS CORP. 2004-03-11 US claimed
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 US disclosed
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 US disclosed
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 US disclosed
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 US disclosed
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 US disclosed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US disclosed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PTGER4, ALKBH3, PIGO GRM2 653/4885NPC1 2124/4885RAB9A 4198/4885
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PAOX, ALKBH3, PTGER4 GRM2 1078/4885NPC1 2388/4885RAB9A 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.