Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619345 | 0.87 | EGLN3 (0.42) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11344957 | 0.85 | POLB (0.33) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11096568 | 0.85 | EGLN3 (0.47) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10332748 | 0.83 | EGLN3 (0.42) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27975527 | 0.83 | EGLN3 (0.42) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1968152 | 0.82 | TSHR (0.47) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10407825 | 0.81 | EGLN3 (0.40) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11244290 | 0.78 | FDPS (0.34) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11244294 | 0.78 | FDPS (0.34) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10729444 | 0.77 | EGLN3 (0.42) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223327-B1 | TRIAZOLYLMETHYL-TERT.-BUTYL-CARBINOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-16 | — | — | EP | disclosed |
| US-4999043-A | Triazolylmethyl tert-butyl carbinol derivatives which have plant growth regulating properties | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-12 | — | — | US | disclosed |
| EP-0212841-B1 | SUBSTITUTED HYDROXYBUTYNYL AZOLES AS PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-29 | — | — | EP | disclosed |
| US-4931082-A | Triazole derivatives useful as plant growth regulating agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-05 | — | — | US | disclosed |
| US-4895589-A | TRIAZOLE, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-23 | — | — | US | disclosed |
| US-4818762-A | POWDERY MILDEW ON BARLEY; RUSTS ON WHEAT AND BEANS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | disclosed |
| US-4715887-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | disclosed |
| US-4711657-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0223142-A1 | (-)-Antipodes of (E)-1-(4-chlorophenyl)-5-fluoro-4,4-dimethyl-3-hydroxy-2(1,2,4-triazole-1-yl)-pent-1-ene | BAYER AG (DE) | 1987-05-27 | — | — | EP | disclosed |
| EP-0223327-A1 | Triazolylmethyl-tert.-butyl-carbinol derivatives, processes for their preparation and their use as plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-27 | — | — | EP | disclosed |
| EP-0108995-A1 | Hydroxyalkinyl-azolyl derivatives | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| US-4427672-A | Combating fungi with substituted triazolylalkyl pyridyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-24 | — | — | US | disclosed |
| EP-0032200-B1 | SUBSTITUTED TRIAZOLYLMETHYL-TERT.-BUTYL-CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS AS WELL AS INTERMEDIATES | BAYER AG (DE) | 1983-07-13 | — | — | EP | disclosed |
| EP-0031911-B1 | SUBSTITUTED TRIAZOLYLMETHYL-TERT.-BUTYL-KETONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS AS WELL AS INTERMEDIATES | BAYER AG (DE) | 1982-11-17 | — | — | EP | disclosed |
| US-4344953-A | INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0045016-A1 | Triazolylalkyl-pyridyl ethers, their preparation and use as fungicides | BAYER AG (DE) | 1982-02-03 | — | — | EP | disclosed |
| EP-0005249-B1 | SUBSTITUTED ALKANYL-AZOLYL CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES, ACARICIDES AND NEMATOCIDES | BAYER AG (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0032200-A1 | Substituted triazolylmethyl-tert.-butyl-carbinols, process for their preparation and their use as plant protecting agents as well as intermediates | BAYER AG (DE) | 1981-07-22 | — | — | EP | disclosed |
| EP-0031911-A2 | Substituted triazolylmethyl-tert.-butyl-ketones, process for their preparation and their use as plant protecting agents as well as intermediates | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| EP-0005249-A2 | Substituted alkanyl-azolyl carbamates, process for their preparation and their use as insecticides, acaricides and nematocides | BAYER AG (DE) | 1979-11-14 | — | — | EP | disclosed |