Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL539064 | 0.79 | ALDH1A1 (0.60) | TSHRMAPTALDH1A1HTTPOLB | |
| SCHEMBL65293 | 0.79 | CYP19A1 (0.62) | TSHRMAPTALDH1A1HTTPOLB | |
| SCHEMBL15720733 | 0.77 | KMT2A (0.47) | TSHRMAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL17160442 | 0.77 | KMT2A (0.47) | TSHRMAPTALDH1A1HTTPOLB | |
| SCHEMBL249094 | 0.77 | MAPT (0.44) | TSHRMAPTALDH1A1HTTCYP3A4 | |
| SCHEMBL22032825 | 0.77 | ALDH1A1 (0.46) | TSHRMAPTALDH1A1HTTNPC1 | |
| SCHEMBL3924064 | 0.74 | LMNA (0.46) | TSHRMAPTHTTPOLBCYP3A4 | |
| SCHEMBL5538329 | 0.74 | CYP19A1 (0.62) | TSHRMAPTALDH1A1HTTPOLB | |
| SCHEMBL1396 | 0.74 | TSHR (0.78) | TSHRMAPTALDH1A1HTTPOLB | |
| SCHEMBL17265773 | 0.73 | ALDH1A1 (0.52) | TSHRMAPTALDH1A1NPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5022738-A | Optical fiber nonlinear wavelength modulator device | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0420156-A1 | Wavelength modulator device | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |