SCHEMBL9770756

SCHEMBL9770756

Cc1cc2c(cc1C)C(C)(C)CC2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 14/20 0.41
RXRG P48443 9/20 0.41
RXRB P28702 8/20 0.41
RARA P10276 3/20 0.35
RARB P10826 2/20 0.35
RARG P13631 2/20 0.35
ESR1 P03372 2/20 0.33
MEN1 O00255 1/20 0.33
CYP26A1 O43174 1/20 0.33
ABCB11 O95342 1/20 0.33
PGR P06401 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
TBXA2R P21731 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29518297 1.00 RXRA (0.41) RXRARXRGRXRBRARARARB
SCHEMBL22589962 0.85 ESR1 (0.35) RXRARXRGRXRBRARBESR1
SCHEMBL10323390 0.84 RXRA (0.40) RXRARXRGRXRBRARARARB
SCHEMBL4226427 0.84 RXRA (0.40) RXRARXRGRXRBESR1MEN1
SCHEMBL4654263 0.81 RXRA (0.37) RXRARXRGRXRBADORA3CHRM1
SCHEMBL1496270 0.81 MAPT (0.38) RXRARXRGRXRBALDH1A1CYP3A4
SCHEMBL14499144 0.79 RXRA (0.41) RXRARXRGRXRBESR1ESR2
SCHEMBL18741265 0.78 RXRA (0.52) RXRARXRGRXRBRARARARB
SCHEMBL18741055 0.78 RXRA (0.52) RXRARXRGRXRBRARARARB
SCHEMBL7622765 0.78 RXRA (0.48) RXRARXRGRXRBRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048316-B2 Sweetener and flavor compositions, methods of making and methods of use thereof EPC NATURAL PRODUCTS CO., LTD. (CN) 2024-07-30 US disclosed
US-12029228-B2 Sweetener and flavor compositions, methods of making and methods of use thereof EPC Natural Products Co., Ltd (CN) 2024-07-09 US disclosed
US-11985994-B2 Sweetener and flavor compositions, methods of making and methods of use thereof EPC Natural Products Co., Ltd (CN) 2024-05-21 US disclosed
US-11849742-B2 Tasteful natural sweetener and flavor EPC NATURAL PRODUCTS CO., LTD. (CN) 2023-12-26 US disclosed
CN-116965585-A Tobacco leaf fermentation method based on biological fermentation enzyme 菀之源生物科技(深圳)有限公司 2023-10-31 CN disclosed
US-11793218-B2 Sweetener and flavor compositions, methods of making and methods of use thereof EPC NATURAL PRODUCTS CO., LTD. (CN) 2023-10-24 US disclosed
EP-4223146-A1 SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF EPC Natural Products Co., Ltd. (CN) 2023-08-09 EP disclosed
US-20230082165-A1 TASTEFUL NATURAL SWEETENER AND FLAVOR EPC Natural Products Co., Ltd (CN) 2023-03-16 US disclosed
US-20230085263-A1 TASTEFUL NATURAL SWEETENER AND FLAVOR EPC Natural Products., Ltd. (CN) 2023-03-16 US disclosed
US-20230060800-A1 SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF EPC Natural Products Co., Ltd (CN) 2023-03-02 US disclosed
WO-2019217310-A1 SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF EPC NATURAL PRODUCTS CO., LTD. (CN) 2019-11-14 WO disclosed
WO-2019217258-A1 A TASTEFUL NATURAL SWEETENER AND FLAVOR EPC NATURAL PRODUCTS CO., LTD. (CN) 2019-11-14 WO disclosed
WO-2019217312-A1 SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF EPC NATURAL PRODUCTS CO., LTD. (CN) 2019-11-14 WO disclosed
US-10085473-B2 Purification of Luo Han Guo extract TATE & LYLE INGREDIENTS AMERICAS LLC (US) 2018-10-02 US disclosed
CN-106483229-A In a kind of Nicotiana tabacum L. by water distillation and extraction, volatility causes perfumery to build method and the application of Nicotiana tabacum L. finger printing 中国烟草总公司广东省公司 2017-03-08 CN disclosed
US-20170035085-A1 PURIFICATION OF LUO HAN GUO EXTRACT TATE & LYLE INGREDIENTS AMERICAS LLC (US) 2017-02-09 US disclosed
US-9474295-B2 Purification of Luo Han Guo extract TATE & LYLE INGREDIENTS AMERICAS LLC (US) 2016-10-25 US disclosed
US-8962698-B2 Rebaudioside-mogroside V blends TATE & LYLE INGREDIENTS AMERICAS LLC (US) 2015-02-24 US disclosed
US-20120264831-A1 REBAUDIOSIDE-MOGROSIDE V BLENDS TATE & LYLE INGREDIENTS AMERICAS LLC (US) 2012-10-18 US disclosed
US-4987261-A Diaminoindane derivatives MITSUI TOATSU CHEMICALS, INC. (JP) 1991-01-22 US disclosed