Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770983 | 0.91 | POLB (0.31) | POLBALDH1A1HPGDHTTTP53 | |
| SCHEMBL8562173 | 0.88 | ALDH1A1 (0.32) | POLBALDH1A1HPGDHTTTP53 | |
| SCHEMBL9770833 | 0.88 | ALDH1A1 (0.32) | ALDH1A1GAA | |
| SCHEMBL8562171 | 0.88 | ALDH1A1 (0.32) | POLBALDH1A1HPGDHTTTP53 | |
| SCHEMBL9770986 | 0.87 | ALDH1A1 (0.34) | ALDH1A1HPGDGAATSHR | |
| SCHEMBL10583196 | 0.82 | ALDH1A1 (0.32) | POLBALDH1A1HPGDHTTTP53 | |
| SCHEMBL10583190 | 0.82 | ALDH1A1 (0.32) | POLBALDH1A1HPGDHTTTP53 | |
| SCHEMBL9771013 | 0.79 | POLB (0.33) | POLBALDH1A1GAA | |
| SCHEMBL9770889 | 0.78 | ALDH1A1 (0.34) | ALDH1A1HPGDGAAMAPTTSHR | |
| SCHEMBL9770975 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | claimed |
| EP-0304920-A2 | Condensed heterocyclic derivatives, process for their production and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-01 | — | — | EP | claimed |