Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771013 | 0.92 | POLB (0.33) | ALDH1A1GAAL3MBTL1KMT2A | |
| SCHEMBL9770986 | 0.91 | ALDH1A1 (0.34) | ALDH1A1HSD17B10HPGDGAATDP1 | |
| SCHEMBL9770983 | 0.87 | POLB (0.31) | ALDH1A1HPGDGAAMAPT | |
| SCHEMBL9770876 | 0.84 | BAZ2B (0.34) | ALDH1A1HSD17B10HPGDGAAMAPT | |
| SCHEMBL9770833 | 0.82 | ALDH1A1 (0.32) | ALDH1A1GAAKMT2A | |
| SCHEMBL9824563 | 0.80 | GAA (0.37) | ALDH1A1HSD17B10HPGDGAATDP1 | |
| SCHEMBL9824569 | 0.80 | GAA (0.37) | ALDH1A1HSD17B10HPGDGAATDP1 | |
| SCHEMBL9551231 | 0.80 | ALDH1A1 (0.36) | ALDH1A1HSD17B10HPGDGAATDP1 | |
| SCHEMBL9770845 | 0.78 | POLB (0.32) | ALDH1A1HPGDGAAMAPTTSHR | |
| SCHEMBL9770930 | 0.77 | KMT2A (0.33) | ALDH1A1GAATDP1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | claimed |
| EP-0304920-A2 | Condensed heterocyclic derivatives, process for their production and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-01 | — | — | EP | claimed |