Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21143365 | 0.88 | CYP4F2 (0.50) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL6444519 | 0.84 | MAPT (0.50) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL28872467 | 0.83 | MAPT (0.50) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL7783361 | 0.83 | TDP1 (0.51) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL5375254 | 0.83 | TDP1 (0.53) | ALDH1A1TSHRGAAKMT2AHSD17B10 | |
| SCHEMBL109308 | 0.82 | ALDH1A1 (0.61) | ADRB2ADRB1ADRB3ALDH1A1TSHR | |
| SCHEMBL7219097 | 0.81 | ALDH1A1 (0.67) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL4945712 | 0.81 | TDP1 (0.56) | MAPTALDH1A1TSHRGAAKMT2A | |
| SCHEMBL12136734 | 0.81 | PRSS1 (0.55) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL5382671 | 0.81 | MAPT (0.66) | ADRB2ADRB1ADRB3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990690-A | Catalytic hydrocracking of an aroomatic carboxylic acid ester | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-02-05 | — | — | US | disclosed |