Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 9/20 | 0.38 |
| ▸ | HTR1A | P08908 | 9/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | ACACB | O00763 | 7/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770789 | 0.92 | HTR1A (0.36) | DRD4HTR1AKCNH2ADRB2ADRB1 | |
| SCHEMBL9770814 | 0.88 | GLA (0.40) | ALOX5APDRD4GLAADRB2ADRB1 | |
| SCHEMBL9770929 | 0.87 | HTR1A (0.37) | DRD4HTR1AKCNH2ADRB2ADRB1 | |
| SCHEMBL8880246 | 0.85 | ALOX5AP (0.36) | ALOX5APHTR1AGLAADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL10505873 | 0.82 | CHRM2 (0.55) | ALOX5APHTR1AGLAADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL10505879 | 0.82 | ALOX5AP (0.44) | ALOX5APDRD4HTR1AGLAADRB2 | |
| SCHEMBL8880254 | 0.82 | MEN1 (0.36) | ALOX5APGLAADRB2ADRB1ADRB3 | |
| SCHEMBL8880433 | 0.82 | ALOX5AP (0.38) | ALOX5APHTR1AGLAADRB2ADRB1 | |
| SCHEMBL8880440 | 0.81 | KMT2A (0.35) | ALOX5APGLAADRB2ADRB1ADRB3 | |
| SCHEMBL8879820 | 0.81 | GLA (0.37) | GLAADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | disclosed |
| EP-0334146-A1 | Morpholines and morpholine-N-oxides, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |