Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770789 | 0.88 | HTR1A (0.36) | HTR1ACHRM2DRD3HTR2BACACB | |
| SCHEMBL9770796 | 0.87 | ADRB2 (0.37) | PPARGPPARAADRB2ADRB1ADRB3 | |
| SCHEMBL9770957 | 0.87 | ALOX5AP (0.38) | HTR1ACHRM2DRD3HTR2BACACB | |
| SCHEMBL8881673 | 0.84 | ADRB1 (0.33) | HTR1ACHRM2DRD3HTR2BACACB | |
| SCHEMBL9770835 | 0.81 | SLC2A1 (0.35) | PPARGPPARAADRB2ADRB1ADRB3 | |
| SCHEMBL8879419 | 0.80 | HRH3 (0.36) | PPARGPPARAADRB2ADRB1ADRB3 | |
| SCHEMBL8881426 | 0.80 | PPARG (0.35) | PPARGPPARAADRB2ADRB1ADRB3 | |
| SCHEMBL8880353 | 0.78 | MEN1 (0.32) | HTR1ACHRM2DRD3HTR2BADRB1 | |
| SCHEMBL9770964 | 0.77 | SLC5A2 (0.35) | ACACBPPARGPPARADRD4HRH3 | |
| SCHEMBL9770815 | 0.75 | HRH3 (0.42) | ACACBKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | disclosed |
| EP-0334146-A1 | Morpholines and morpholine-N-oxides, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |