Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182705 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL5491075 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL1270718 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL9774371 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL5485130 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL21306480 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL367595 | 0.73 | TYR (0.58) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL6281528 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL1647492 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8TYRPTGS2 | |
| SCHEMBL1140933 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8TYRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3014589-A | — | — | None | — | — | JP | disclosed |
| JP-H0314589-A | UNSATURATED GROUP-CONTAINING ORGANOSILICON COMPOUND | TOSHIBA SILICONE CO LTD | 1991-01-23 | — | — | JP | disclosed |