Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772245 | 0.90 | HTT (0.56) | TGM2HTTFOLH1DPP8DPP7 | |
| SCHEMBL9772251 | 0.90 | HTT (0.56) | TGM2HTTFOLH1DPP8DPP7 | |
| SCHEMBL9772191 | 0.86 | HTT (0.64) | TGM2HTTFOLH1DPP8DPP7 | |
| SCHEMBL9772192 | 0.86 | HTT (0.64) | TGM2HTTFOLH1DPP8DPP7 | |
| SCHEMBL9772263 | 0.85 | TGM2 (0.57) | SIRT2TGM2HTTFOLH1DPP8 | |
| SCHEMBL3697193 | 0.84 | TGM2 (0.56) | SIRT2SIRT1TGM2HTTFOLH1 | |
| SCHEMBL9772187 | 0.83 | HTT (0.58) | TGM2HTTFOLH1DPP8DPP7 | |
| SCHEMBL11758185 | 0.83 | HTT (0.58) | SIRT2SIRT1TGM2HTTFOLH1 | |
| SCHEMBL6421454 | 0.83 | TGM2 (0.58) | TGM2HTTFOLH1DPP8DPP7 | |
| SCHEMBL11000431 | 0.83 | HTT (0.58) | TGM2HTTFOLH1DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983328-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1991-01-08 | — | — | US | disclosed |
| US-4518532-A | ANTITIMOR | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-05-21 | — | — | US | disclosed |