Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.60 |
| ▸ | HTR1A | P08908 | 5/20 | 0.60 |
| ▸ | HTR2A | P28223 | 5/20 | 0.60 |
| ▸ | HTR2B | P41595 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.60 |
| ▸ | HTR1D | P28221 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | HTR1B | P28222 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.60 |
| ▸ | HTR3B | O95264 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | HTR1E | P28566 | 1/20 | 0.60 |
| ▸ | HTR1F | P30939 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | HTR3A | P46098 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1102333 | 0.87 | HTR2C (0.61) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL21207296 | 0.84 | HTR2C (0.54) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL6716510 | 0.84 | NPSR1 (0.59) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL11387363 | 0.84 | NPSR1 (0.59) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL6716504 | 0.84 | NPSR1 (0.59) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL27659097 | 0.84 | HPGD (0.54) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| Hydrochloric Acid SCHEMBL27549572 | 0.83 | HPGD (0.52) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL4510688 | 0.81 | GPR84 (0.63) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL10940983 | 0.81 | GPR84 (0.63) | HTR2CHTR1AHTR2AHTR2BHTR1D | |
| SCHEMBL14527163 | 0.81 | MPO (0.64) | HTR2CHTR1AHTR2ATSHRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030640-A | Alpha-heterocyclic ethanolamino alkylindoles, growth promoters and feed efficiency agents for animals, bronchodilators, antidepressants, antiobesity agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0377488-A1 | Novel beta-adrenergic agonists | MERCK & CO. INC. (US) | 1990-07-11 | — | — | EP | disclosed |