Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773092 | 1.00 | ADRB3 (0.49) | ADRB3ADRB2MEN1KMT2ALTA4H | |
| SCHEMBL9772978 | 1.00 | ADRB3 (0.49) | ADRB3ADRB2MEN1KMT2ALTA4H | |
| SCHEMBL9773015 | 0.88 | ADRB3 (0.52) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9773025 | 0.88 | ADRB3 (0.52) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9773100 | 0.88 | ADRB3 (0.52) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9773081 | 0.85 | ADRB3 (0.58) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9773077 | 0.85 | ADRB3 (0.58) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9773063 | 0.81 | LTA4H (0.53) | ADRB3ADRB2MEN1KMT2ALTA4H | |
| SCHEMBL9773034 | 0.81 | LTA4H (0.53) | ADRB3ADRB2MEN1KMT2ALTA4H | |
| SCHEMBL9773026 | 0.81 | LTA4H (0.53) | ADRB3ADRB2MEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030640-A | Alpha-heterocyclic ethanolamino alkylindoles, growth promoters and feed efficiency agents for animals, bronchodilators, antidepressants, antiobesity agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | disclosed |