Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773025 | 1.00 | ADRB3 (0.52) | ADRB3ADRB1ADRB2HTR6HTR1A | |
| SCHEMBL9773015 | 1.00 | ADRB3 (0.52) | ADRB3ADRB1ADRB2HTR6HTR1A | |
| SCHEMBL9773092 | 0.88 | ADRB3 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9772964 | 0.88 | ADRB3 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9772978 | 0.88 | ADRB3 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9773081 | 0.87 | ADRB3 (0.58) | ADRB3ADRB1ADRB2HTR6 | |
| SCHEMBL9773077 | 0.87 | ADRB3 (0.58) | ADRB3ADRB1ADRB2HTR6 | |
| SCHEMBL9772979 | 0.84 | CYP2D6 (0.49) | ADRB3HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL9772953 | 0.84 | CYP2D6 (0.49) | ADRB3HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL9773044 | 0.78 | ADRB3 (0.56) | ADRB3ADRB1ADRB2HTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030640-A | Alpha-heterocyclic ethanolamino alkylindoles, growth promoters and feed efficiency agents for animals, bronchodilators, antidepressants, antiobesity agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | disclosed |