Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271357 | 1.00 | ACE (0.57) | ACENOD1FAAHACE2GPR84 | |
| SCHEMBL7271367 | 1.00 | ACE (0.57) | ACENOD1FAAHACE2GPR84 | |
| SCHEMBL9702204 | 1.00 | ACE (0.57) | ACENOD1FAAHACE2GPR84 | |
| SCHEMBL9773243 | 1.00 | ACE (0.57) | ACENOD1FAAHACE2GPR84 | |
| Fumaric Acid SCHEMBL7270438 | 0.93 | ACE (0.52) | ACENOD1FAAHACE2GPR84 | |
| Maleic Acid SCHEMBL7270427 | 0.93 | ACE (0.52) | ACENOD1FAAHACE2GPR84 | |
| SCHEMBL300278 | 0.87 | ACE (0.49) | ACEKMT2A | |
| SCHEMBL4650239 | 0.87 | ACE (0.49) | ACEKMT2A | |
| SCHEMBL13482629 | 0.87 | ACE (0.49) | ACEKMT2A | |
| SCHEMBL4458272 | 0.87 | ACE (0.49) | ACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043346-A | Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0338508-A2 | Esters from amino-acids, their preparation process, drugs containing same and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | disclosed |