Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CTSG | P08311 | 2/20 | 0.48 |
| ▸ | CMA1 | P23946 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.48 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773257 | 1.00 | ACE (0.51) | ACECTSGCMA1SIRT2SIRT1 | |
| SCHEMBL9773262 | 1.00 | ACE (0.51) | ACECTSGCMA1SIRT2SIRT1 | |
| SCHEMBL9773198 | 0.90 | ACE (0.52) | ACECTSGCMA1BIRC2 | |
| SCHEMBL9773172 | 0.90 | ACE (0.52) | ACECTSGCMA1BIRC2 | |
| SCHEMBL7439231 | 0.89 | TACR1 (0.58) | ACETACR1 | |
| SCHEMBL9773203 | 0.88 | ACE (0.58) | ACESIRT2SIRT1SIRT3 | |
| SCHEMBL9773176 | 0.88 | ACE (0.58) | ACESIRT2SIRT1SIRT3 | |
| SCHEMBL9703183 | 0.88 | ACE (0.58) | ACESIRT2SIRT1SIRT3 | |
| SCHEMBL10958280 | 0.83 | SIRT2 (0.53) | ACESIRT2SIRT1SIRT3 | |
| SCHEMBL10420650 | 0.82 | TACR1 (0.57) | ACETACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043346-A | Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0338508-A2 | Esters from amino-acids, their preparation process, drugs containing same and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | disclosed |