Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420650 | 0.92 | TACR1 (0.57) | TACR1POLBCTSLCTSBCTSS | |
| SCHEMBL10969556 | 0.92 | TACR1 (0.53) | TACR1POLBMMP8CTSLELANE | |
| SCHEMBL1849290 | 0.89 | MMP8 (0.56) | TACR1POLBMMP8ELANEHPRT1 | |
| SCHEMBL9773257 | 0.89 | ACE (0.51) | TACR1ACE | |
| SCHEMBL9773262 | 0.89 | ACE (0.51) | TACR1ACE | |
| SCHEMBL9773259 | 0.89 | ACE (0.51) | TACR1ACE | |
| SCHEMBL5869726 | 0.88 | FOLH1 (0.51) | TACR1CTSLCTSBCTSKACE | |
| SCHEMBL5870079 | 0.88 | CTSK (0.48) | TACR1POLBCTSLCTSBCTSK | |
| SCHEMBL5869730 | 0.88 | FOLH1 (0.51) | TACR1CTSLCTSBCTSKACE | |
| SCHEMBL5870077 | 0.88 | CTSK (0.48) | TACR1POLBCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |