Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.40 |
| ▸ | AMD1 | P17707 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979014 | 0.77 | CYP2C9 (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30413037 | 0.77 | CYP2C9 (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2327463 | 0.76 | ADORA2A (0.55) | ADORA2AADORA1 | |
| SCHEMBL29870529 | 0.74 | ADORA2A (0.65) | MAPTALDH1A1CSNK1A1CLK4ADORA2A | |
| SCHEMBL978983 | 0.74 | ADORA2A (0.65) | MAPTALDH1A1CSNK1A1CLK4ADORA2A | |
| SCHEMBL29870155 | 0.74 | ADORA2A (0.52) | CSNK1A1CLK4ADORA2AADORA1SCN5A | |
| SCHEMBL979235 | 0.74 | ADORA2A (0.52) | CSNK1A1CLK4ADORA2AADORA1SCN5A | |
| SCHEMBL2324088 | 0.73 | ADORA2A (0.64) | ADORA2AADORA1 | |
| SCHEMBL12948664 | 0.70 | ADORA2A (0.47) | CSNK1A1CLK4ADORA2AADORA1HSD17B10 | |
| SCHEMBL978735 | 0.70 | MAOB (0.47) | CSNK1A1CLK4ADORA2AADORA1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307273-B1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | UNIV GREENWICH (GB) | 2020-12-09 | — | — | EP | claimed |
| US-10576086-B2 | Triazine derivatives as interferon-gamma inhibitors | UNIVERSITY OF GREENWICH (GB) | 2020-03-03 | — | — | US | claimed |
| US-20180169105-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | UNIVERSITY OF GREENWICH (GB) | 2018-06-21 | — | — | US | claimed |
| EP-3307273-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | University of Greenwich (GB) | 2018-04-18 | — | — | EP | claimed |
| US-9862691-B2 | Cyclic triazo and diazo sodium channel blockers | UNIVERSITY OF GREENWICH (GB) | 2018-01-09 | — | — | US | claimed |
| WO-2016198878-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | UNIVERSITY OF GREENWICH (GB) | 2016-12-15 | — | — | WO | claimed |
| US-20160311784-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIVERSITY OF GREENWICH (GB) | 2016-10-27 | — | — | US | claimed |
| EP-3002280-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | University of Greenwich (GB) | 2016-04-06 | — | — | EP | claimed |
| US-20140155403-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIVERSITY OF GREENWICH (GB) | 2014-06-05 | — | — | US | claimed |
| EP-3002280-B1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIV GREENWICH (GB) | 2023-05-24 | — | — | EP | disclosed |
| EP-3307273-B1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | UNIV GREENWICH (GB) | 2020-12-09 | — | — | EP | disclosed |
| US-10576086-B2 | Triazine derivatives as interferon-gamma inhibitors | UNIVERSITY OF GREENWICH (GB) | 2020-03-03 | — | — | US | disclosed |
| US-20180169105-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | UNIVERSITY OF GREENWICH (GB) | 2018-06-21 | — | — | US | disclosed |
| EP-3307273-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | University of Greenwich (GB) | 2018-04-18 | — | — | EP | disclosed |
| EP-3002280-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | University of Greenwich (GB) | 2016-04-06 | — | — | EP | disclosed |
| EP-2229371-B1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIV GREENWICH (GB) | 2015-12-23 | — | — | EP | disclosed |
| US-20140155403-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIVERSITY OF GREENWICH (GB) | 2014-06-05 | — | — | US | disclosed |
| US-20110009413-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIVERSITY OF GREENWICH (GB) | 2011-01-13 | — | — | US | disclosed |
| EP-2229371-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | University of Greenwich (GB) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009090431-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIVERSITY OF GREENWICH (GB) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155403-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | SCN1A, SCN1B, SCN3A | MAPT 3296/4885ALDH1A1 1806/4885CSNK1A1 719/4885 |
| US-20110009413-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | CACNA1E, SCN2B, SCN3A | MAPT 239/4885ALDH1A1 3145/4885CSNK1A1 4578/4885 |
| US-10576086-B2 | Triazine derivatives as interferon-gamma inhibitors | IFNG, IFNAR1, IRF3 | MAPT 18/4885ALDH1A1 1809/4885CSNK1A1 599/4885 |
| US-20180169105-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | IFNG, IFNAR1, IRF3 | MAPT 18/4885ALDH1A1 1809/4885CSNK1A1 599/4885 |
| US-20160311784-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | SCN1A, SCN1B, SCN3A | MAPT 3135/4885ALDH1A1 1729/4885CSNK1A1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.