SCHEMBL9773597

SCHEMBL9773597

Cc1c(C2(c3ccccc3N(C)C)OC(=O)c3ccccc32)c2ccccc2n1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.41
NPSR1 Q6W5P4 3/20 0.41
CFTR P13569 1/20 0.39
GOPC Q9HD26 1/20 0.39
MAPT P10636 5/20 0.38
POLB P06746 4/20 0.38
GPR55 Q9Y2T6 2/20 0.38
ALOX12 P18054 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP2C19 P33261 3/20 0.36
GAA P10253 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 2/20 0.36
HTT P42858 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31628403 0.88 LMNA (0.49) LMNANPSR1CFTRGOPCMAPT
SCHEMBL3219191 0.88 LMNA (0.49) LMNANPSR1CFTRGOPCMAPT
SCHEMBL9286826 0.87 KDM4E (0.39) LMNANPSR1MAPTPOLBMEN1
SCHEMBL29385861 0.84 TDP1 (0.50) LMNANPSR1CFTRGOPCMAPT
SCHEMBL395450 0.84 TDP1 (0.50) LMNANPSR1CFTRGOPCMAPT
SCHEMBL11262222 0.84 HPGD (0.50) LMNANPSR1MAPTPOLBGPR55
SCHEMBL21443997 0.82 LMNA (0.44) LMNANPSR1CFTRGOPCMAPT
SCHEMBL10937717 0.80 LMNA (0.41) LMNANPSR1CFTRGOPCMAPT
SCHEMBL1347314 0.80 HPGD (0.55) LMNANPSR1MAPTPOLBGPR55
SCHEMBL29411207 0.80 HPGD (0.43) LMNANPSR1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5008231-A Color forming material, developer, pigment overcoat and binder KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-04-16 US disclosed
EP-0015133-A2 Pressure sensitive copying system Mitsubishi Paper Mills, Ltd. (JP) 1980-09-03 EP disclosed