SCHEMBL3219191

SCHEMBL3219191

Cc1c(C2(c3c(C)n(C)c4ccccc34)OC(=O)c3ccccc32)c2ccccc2n1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.49
NPSR1 Q6W5P4 4/20 0.49
CFTR P13569 1/20 0.46
GOPC Q9HD26 1/20 0.46
MAPT P10636 5/20 0.44
POLB P06746 3/20 0.44
GPR55 Q9Y2T6 2/20 0.44
ALOX12 P18054 1/20 0.44
GAA P10253 3/20 0.43
CYP2C19 P33261 3/20 0.43
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
HTT P42858 2/20 0.43
GLA P06280 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31628403 1.00 LMNA (0.49) LMNANPSR1CFTRGOPCMAPT
SCHEMBL21443997 0.94 LMNA (0.44) LMNANPSR1CFTRGOPCMAPT
SCHEMBL10937717 0.91 LMNA (0.41) LMNANPSR1CFTRGOPCMAPT
SCHEMBL8009686 0.89 KDM4E (0.41) LMNANPSR1CFTRGOPCMAPT
SCHEMBL9773597 0.88 LMNA (0.41) LMNANPSR1CFTRGOPCMAPT
SCHEMBL395450 0.86 TDP1 (0.50) LMNANPSR1CFTRGOPCMAPT
SCHEMBL29385861 0.86 TDP1 (0.50) LMNANPSR1CFTRGOPCMAPT
SCHEMBL18516808 0.86 CNR2 (0.44) MAPTALDH1A1KDM4EHTT
SCHEMBL9618089 0.85 LMNA (0.40) LMNANPSR1CFTRGOPCMAPT
SCHEMBL4226829 0.83 LMNA (0.40) LMNANPSR1CFTRGOPCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025013922-A1 ON-PRESS DEVELOPMENT-TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR, PLANOGRAPHIC PRINTING PLATE PRODUCTION METHOD, AND PLANOGRAPHIC PRINTING METHO 富士フイルム株式会社 2025-01-16 WO disclosed
WO-2025013910-A1 ON-PRESS DEVELOPMENT TYPE PLANOGRAPHIC PRINTING PLATE ORIGINAL PLATE, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, PLANOGRAPHIC PRINTING METHOD, AND COMPOUND 富士フイルム株式会社 2025-01-16 WO disclosed
US-11667564-B2 Method of manufacturing an etched glass article AGFA-GEVAERT NV (BE) 2023-06-06 US disclosed
US-20210017068-A1 METHOD OF MANUFACTURING AN ETCHED GLASS ARTICLE AGFA-GEVAERT NV (BE) 2021-01-21 US disclosed
US-20200165193-A1 A DEVELOPING AGENT PRECURSOR FOR LASER MARKABLE COMPOSITIONS AGFA-GEVAERT NV (BE) 2020-05-28 US disclosed
US-10662532-B2 Methods of manufacturing embossing elements AGFA-GEVAERT N.V. (BE) 2020-05-26 US disclosed
US-10286708-B2 Laser markable compositions, articles and documents AGFA-GEVAERT (BE) 2019-05-14 US disclosed
US-10272708-B2 Thermosensitive recording material and method for manufacturing the same FUJIFILM CORPORATION (JP) 2019-04-30 US disclosed
US-10265995-B2 Laser markable security articles and documents AGFA-GEVAERT (BE) 2019-04-23 US disclosed
US-10245866-B2 Colour imaging of security document precursors AGFA-GEVAERT (BE) 2019-04-02 US disclosed
EP-0012579-A2 Pressure-sensitive mark-recording systems and solutions for use in such systems MONSANTO EUROPE S.A./N.V. (BE) 1980-06-25 EP disclosed
US-4130299-A AROMATIC HYDROCARBON MONSANTO COMPANY (US) 1978-12-19 US disclosed
US-4124526-A Encapsulation process and resulting aqueous dispersion of encapsulated droplets MONSANTO COMPANY (US) 1978-11-07 US disclosed
US-4093278-A PRESSURE RELEASE ARYL ESTER SOLVENT MONSANTO COMPANY (US) 1978-06-06 US disclosed
US-4074050-A COLOR FORMER HODOGAYA CHEMICAL CO., LTD. (JA) 1978-02-14 US disclosed
US-4073614-A Mixture of benzoxazines and benzodioxanes which may be used as color formers HODOGAYA CHEMICAL CO., LTD. (JA) 1978-02-14 US disclosed
US-3979327-A PARTIALLY HYDROGENATED TERPHENYL MONSANTO COMPANY (US) 1976-09-07 US disclosed
US-3979324-A BENZYLNAPHTHALENE COMPOUND MONSANTO COMPANY (US) 1976-09-07 US disclosed
US-3968320-A Dye solvents for pressure-sensitive record material MONSANTO COMPANY (US) 1976-07-06 US disclosed
US-3968301-A Pressure-sensitive record material and dye solvents therefor MONSANTO COMPANY (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200165193-A1 A DEVELOPING AGENT PRECURSOR FOR LASER MARKABLE COMPOSITIONS RB1, CDK16, CDK19 LMNA 58/4885NPSR1 4638/4885CFTR 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.