SCHEMBL9774476

SCHEMBL9774476

CC(=O)CC(=O)OC[C@H]1CC[C@H](COC(=O)CC(C)=O)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.46
GAA P10253 2/20 0.46
SI P14410 2/20 0.46
MGAM2 Q2M2H8 2/20 0.46
LMNA P02545 2/20 0.44
PTGIR P43119 4/20 0.34
SLC1A3 P43003 2/20 0.32
SLC1A2 P43004 2/20 0.32
SLC1A1 P43005 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
PTGDR Q13258 2/20 0.31
JAK2 O60674 1/20 0.31
JAK1 P23458 1/20 0.31
TYK2 P29597 1/20 0.31
JAK3 P52333 1/20 0.31
POLB P06746 1/20 0.31
PARP15 Q460N3 1/20 0.31
PARP10 Q53GL7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5139018 1.00 MGAM (0.46) MGAMGAASIMGAM2LMNA
SCHEMBL2270476 1.00 MGAM (0.46) MGAMGAASIMGAM2LMNA
SCHEMBL20954311 0.92 LMNA (0.55) MGAMGAASIMGAM2LMNA
SCHEMBL1322681 0.92 LMNA (0.50) MGAMGAASIMGAM2LMNA
SCHEMBL23048198 0.91 LMNA (0.50) MGAMGAASIMGAM2LMNA
SCHEMBL13425332 0.90 LMNA (0.58) MGAMGAASIMGAM2LMNA
SCHEMBL9933380 0.88 ALDH1A1 (0.49) MGAMGAASIMGAM2LMNA
SCHEMBL20954558 0.87 MGAM (0.39) MGAMGAASIMGAM2LMNA
SCHEMBL20185683 0.84 LMNA (0.43) MGAMGAASIMGAM2LMNA
SCHEMBL20954635 0.82 LMNA (0.39) MGAMGAASIMGAM2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5017649-A Low temperature crosslinking EASTMAN KODAK COMPANY (US) 1991-05-21 US disclosed