Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.57 |
| ▸ | FEN1 | P39748 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.50 |
| ▸ | WNT3A | P56704 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089515 | 0.81 | CTNNB1 (0.68) | PTPN1ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL14732971 | 0.79 | CTNNB1 (0.61) | PTPN1ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL7244500 | 0.78 | CTNNB1 (0.60) | PTPN1ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL3070244 | 0.78 | CA12 (0.69) | MEN1KMT2ATDP1CES1CA12 | |
| SCHEMBL30758347 | 0.78 | CTNNB1 (0.60) | PTPN1ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL20508992 | 0.77 | PTPN1 (0.74) | PTPN1ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL6383722 | 0.77 | PTPN1 (0.58) | PTPN1ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL8987291 | 0.76 | PTPN1 (0.62) | PTPN1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL9775167 | 0.76 | CA12 (0.57) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL5691811 | 0.76 | PTPN1 (0.72) | PTPN1ERCC5FEN1CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075339-A | Antiinflammatory agents, antiallergens | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-4948813-A | Benzylketone phospholipase A2 inhibitors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-14 | — | — | US | disclosed |