Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23188697 | 0.83 | NPC1 (0.36) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL1627210 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL9235153 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL17738012 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL27619400 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL11272569 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL9775182 | 0.78 | PLA2G1B (0.38) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL1627207 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL27671992 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL7016487 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1KMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239728-A2 | Pyridazinone derivatives and the preparation thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-10-07 | — | — | EP | claimed |
| EP-0134439-A1 | Pyridazinone derivatives, preparation thereof and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-20 | — | — | EP | claimed |
| JP-1313468-A | — | — | None | — | — | JP | disclosed |
| JP-1197479-A | — | — | None | — | — | JP | disclosed |
| JP-1180882-A | — | — | None | — | — | JP | disclosed |
| JP-2045471-A | — | — | None | — | — | JP | disclosed |
| CN-116262743-B | Aryl-bi-ring-substituted pyridazinone compound and preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-116262743-A | Aryl-bi-ring-substituted pyridazinone compound and preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-110396083-B | Pyridazinonyl-contained butenolide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-112741095-B | Application of pyridazinone isoxazole methyl sulfide compound as bactericide | 沈阳中化农药化工研发有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-20210300878-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2021-09-30 | — | — | US | disclosed |
| EP-0283271-A2 | Pyridazinone derivative, process for producing thereof and insecticide, acaricide and fungicide containing said derivative as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0134439-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF AND INSECTICIDAL, ACARICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| EP-0239728-A3 | Pyridazinone derivatives and the preparation thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |
| EP-0239728-A2 | Pyridazinone derivatives and the preparation thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0239728-A2 | Pyridazinone derivatives and the preparation thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0232825-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-08-19 | — | — | EP | disclosed |
| EP-0199281-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0183212-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-06-04 | — | — | EP | disclosed |
| EP-0134439-A1 | Pyridazinone derivatives, preparation thereof and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300878-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | TNNI3, TNNT2, FABP3 | SMN1; SMN2 2969/4885NPC1 350/4885KMT2A 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.