Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774203 | 0.87 | PREP (0.46) | KDM4EPREPACE | |
| SCHEMBL9775200 | 0.82 | CYP1A2 (0.50) | PREPACE | |
| SCHEMBL9774299 | 0.81 | PREP (0.47) | NPC1RAB9APREPACE | |
| SCHEMBL10437301 | 0.79 | ACHE (0.39) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL11159378 | 0.77 | ACE (0.53) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL9774278 | 0.77 | ACE (0.54) | SMN1; SMN2HPGDNPC1PREPACE | |
| SCHEMBL9774258 | 0.75 | ACE (0.53) | NPC1RAB9APREPACE | |
| SCHEMBL9774174 | 0.74 | ACE (0.52) | PREPACE | |
| SCHEMBL9403911 | 0.73 | PREP (0.46) | ALDH1A1PREPACE | |
| SCHEMBL9773813 | 0.72 | ACE (0.55) | NPC1RAB9APREPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068242-A | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE FOR PSYCHOTROPIC ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |