Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.70 |
| ▸ | P4HB | P07237 | 3/20 | 0.66 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.62 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977524 | 1.00 | MAOB (1.00) | MAOBCYP1B1CYP1A1P4HBPLIN1 | |
| SCHEMBL2646709 | 0.92 | MAOB (0.84) | MAOBCYP1B1CYP1A1P4HBPLIN1 | |
| SCHEMBL2665141 | 0.92 | MAOB (0.84) | MAOBCYP1B1CYP1A1P4HBPLIN1 | |
| SCHEMBL9779396 | 0.91 | MAOB (0.83) | MAOBCYP1B1CYP1A1P4HBPLIN1 | |
| SCHEMBL3032561 | 0.91 | MAOB (0.83) | MAOBCYP1B1CYP1A1P4HBPLIN1 | |
| SCHEMBL8808974 | 0.87 | MAOB (0.77) | MAOBCYP1B1CYP1A1P4HBMAPT | |
| SCHEMBL8808970 | 0.87 | MAOB (0.77) | MAOBCYP1B1CYP1A1P4HBMAPT | |
| SCHEMBL30504740 | 0.84 | MAOB (0.72) | MAOBCYP1B1CYP1A1P4HBALDH1A1 | |
| SCHEMBL11942091 | 0.84 | P4HB (0.78) | MAOBCYP1B1CYP1A1P4HBLMNA | |
| SCHEMBL24264943 | 0.84 | MAOB (0.70) | MAOBCYP1B1CYP1A1P4HBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284114-A | Method for synthesizing chiral 1, 3-phosphine alcohol | 陕西师范大学 | 2023-06-23 | — | — | CN | disclosed |
| US-8754179-B2 | Light activated shape memory co-polymers | CORNERSTONE RESEARCH GROUP, INC. (US) | 2014-06-17 | — | — | US | disclosed |
| EP-1928827-B1 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS INC (US) | 2012-08-22 | — | — | EP | disclosed |
| US-8217073-B2 | Pyrrole derivatives as therapeutic compounds | MYREXIS, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-7872029-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP | 2011-01-18 | — | — | US | disclosed |
| US-20100216862-A1 | Pyrrole Derivatives As Therapeutic Compounds | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-7714022-B2 | Pyrrole derivatives as therapeutic compounds | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Robinson, Thomas Philip (US) | 2009-01-15 | — | — | US | disclosed |
| US-20080249158-A1 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS, INCORPORATED (US) | 2008-10-09 | — | — | US | disclosed |
| US-7432303-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Bowen, J. Phillip (US) | 2008-10-07 | — | — | US | disclosed |
| US-20080021166-A1 | Light Activated Shape Memory Co-Polymers | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2008-01-24 | — | — | US | disclosed |
| EP-1799771-A2 | LIGHT ACTIVATED SHAPE MEMORY CO-POLYMERS | CORNERSTONE RESEARCH GROUP, INC. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2007001407-A2 | LIGHT ACTIVATED SHAPE MEMORY CO-POLYMERS | CORNERSTONE RESEARCH GROUP, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-6906105-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP (US) | 2005-06-14 | — | — | US | disclosed |
| US-6462075-B1 | USE OF CHALCONE AND ITS DERIVATIVES AS ANTITUMOR/ANTICANCER AGENTS AND TO TREAT A NUMBER OF CONDITIONS OR DISEASE STATES IN WHICH ANGIOGENESIS IS A FACTOR INCLUDING PSORIASIS, ACNE, ROSACEA, WARTS, ECZEMA, HEMANGIOMAS AND LYMPHANGIOGENESIS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2002-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | FLT1, FLT4, VEGFA | MAOB 2526/4885CYP1B1 747/4885CYP1A1 649/4885 |
| US-20100216862-A1 | Pyrrole Derivatives As Therapeutic Compounds | APP, PSEN2, PSEN1 | MAOB 2093/4885CYP1B1 4542/4885CYP1A1 4761/4885 |
| US-20080249158-A1 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | APP, PSEN2, PSEN1 | MAOB 2093/4885CYP1B1 4542/4885CYP1A1 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.