Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.84 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665141 | 1.00 | MAOB (0.84) | MAOBCYP1B1CYP1A1TRPM2P4HB | |
| SCHEMBL977523 | 0.92 | MAOB (1.00) | MAOBCYP1B1CYP1A1P4HBBCHE | |
| SCHEMBL977524 | 0.92 | MAOB (1.00) | MAOBCYP1B1CYP1A1P4HBBCHE | |
| SCHEMBL2646706 | 0.86 | P4HB (0.76) | MAOBCYP1B1CYP1A1P4HBBCHE | |
| SCHEMBL3032561 | 0.83 | MAOB (0.83) | MAOBCYP1B1CYP1A1P4HBBCHE | |
| SCHEMBL9779396 | 0.83 | MAOB (0.83) | MAOBCYP1B1CYP1A1P4HBBCHE | |
| SCHEMBL8808970 | 0.82 | MAOB (0.77) | MAOBCYP1B1CYP1A1P4HBALDH1A1 | |
| SCHEMBL8808974 | 0.82 | MAOB (0.77) | MAOBCYP1B1CYP1A1P4HBALDH1A1 | |
| SCHEMBL30504740 | 0.82 | MAOB (0.72) | MAOBCYP1B1CYP1A1P4HBALDH1A1 | |
| SCHEMBL2664932 | 0.82 | BCHE (0.60) | MAOBCYP1B1P4HBBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463715-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-10-06 | — | — | EP | disclosed |
| US-6762318-B2 | CARBOXYLIC ACID OR TETRAZOLE DERIVATIZED SECONDARY AMIDES; ORAL ADMINISTRATION | NOVO NORDISK A/S (DK) | 2004-07-13 | — | — | US | disclosed |
| US-20030236292-A1 | Stimulant releasing glucose from liver cells; antidiabetic agents | PFIZER INC | 2003-12-25 | — | — | US | disclosed |
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236292-A1 | Stimulant releasing glucose from liver cells; antidiabetic agents | GPR119, GLP1R, GIPR | MAOB 3317/4885CYP1B1 3336/4885CYP1A1 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.