Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13314953 | 0.88 | ATM (0.49) | ALDH1A1SMN1; SMN2ATML3MBTL1 | |
| SCHEMBL14688115 | 0.88 | SMN1; SMN2 (0.54) | ALDH1A1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL26708719 | 0.88 | MAPT (0.60) | ALDH1A1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL30674431 | 0.88 | MAPT (0.60) | ALDH1A1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL4417138 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL4417143 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL7200943 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL23617813 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2ATML3MBTL1 | |
| SCHEMBL9876469 | 0.86 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2ATML3MBTL1 | |
| SCHEMBL7276321 | 0.86 | ERAP2 (0.58) | ALDH1A1HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068242-A | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE FOR PSYCHOTROPIC ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |