SCHEMBL9775280

SCHEMBL9775280

Cc1ccc(S(=O)(=O)n2ccc(C(=O)CCl)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
PKM P14618 1/20 0.51
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
HDAC6 Q9UBN7 1/20 0.47
GRM4 Q14833 1/20 0.47
YAP1 P46937 1/20 0.45
TEAD4 Q15561 1/20 0.45
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13545185 0.87 ALDH1A1 (0.54) ALDH1A1PKMCA1CA2HDAC6
SCHEMBL16795019 0.86 ALDH1A1 (0.52) ALDH1A1PKMCA1CA2HDAC6
SCHEMBL15164809 0.86 ALDH1A1 (0.52) ALDH1A1PKMHDAC6TUBB4ATUBB
SCHEMBL589219 0.85 ALDH1A1 (0.61) ALDH1A1PKMCA1CA2HDAC6
SCHEMBL13891893 0.83 ALDH1A1 (0.50) ALDH1A1PKMCA1CA2HDAC6
Hydrochloric Acid SCHEMBL15974180 0.82 ALDH1A1 (0.49) ALDH1A1PKMCA1CA2HDAC6
SCHEMBL4513102 0.82 ALDH1A1 (0.75) ALDH1A1PKMCA1CA2HDAC6
SCHEMBL1504624 0.82 PKM (0.60) ALDH1A1PKMCA1CA2HDAC6
SCHEMBL13757302 0.81 PKM (0.50) ALDH1A1PKMCA1CA2HDAC6
Hydrochloric Acid SCHEMBL1891433 0.81 PKM (0.59) ALDH1A1PKMCA1CA2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059694-A 3-SUBSTITUTED POLYPYRROLE NIPPON OIL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0396937-A2 3-Substituted polypyrrole NIPPON OIL CO. LTD. (JP) 1990-11-14 EP disclosed