SCHEMBL9775366

SCHEMBL9775366

O=[N+]([O-])c1ccc(O/C(=C(/Oc2ccc([N+](=O)[O-])cc2)C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.53
BCL9 O00512 1/20 0.50
CTNNB1 P35222 1/20 0.50
HSPB1 P04792 1/20 0.50
KMT2A Q03164 3/20 0.49
PKM P14618 1/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MAPK1 P28482 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
THRB P10828 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CA9 Q16790 1/20 0.44
MAPT P10636 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496344 1.00 GAA (0.53) GAABCL9CTNNB1HSPB1KMT2A
SCHEMBL734833 0.84 GAA (0.56) GAABCL9CTNNB1HSPB1KMT2A
Trifluoroacetic Acid SCHEMBL31064275 0.81 GAA (0.53) GAABCL9CTNNB1HSPB1KMT2A
P-Nitrophenol SCHEMBL6226065 0.80 GAA (0.51) GAABCL9CTNNB1HSPB1KMT2A
SCHEMBL5164665 0.78 GAA (0.50) GAABCL9CTNNB1HSPB1KMT2A
SCHEMBL7063519 0.76 GAA (0.65) GAABCL9CTNNB1HSPB1KMT2A
SCHEMBL26374 0.76 GAA (0.65) GAABCL9CTNNB1HSPB1KMT2A
SCHEMBL7398333 0.76 BCL9 (0.60) GAABCL9CTNNB1HSPB1KMT2A
SCHEMBL850563 0.75 GAA (0.47) GAABCL9CTNNB1HSPB1KMT2A
SCHEMBL23084891 0.75 GAA (0.62) GAABCL9CTNNB1HSPB1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990633-A Used as insulating agents BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed