Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325011 | 0.93 | L3MBTL1 (0.42) | L3MBTL1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9326236 | 0.92 | L3MBTL1 (0.44) | L3MBTL1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL23163221 | 0.85 | CYP3A4 (0.46) | L3MBTL1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9545089 | 0.84 | HDAC1 (0.43) | L3MBTL1TSHR | |
| SCHEMBL1751201 | 0.84 | L3MBTL1 (0.69) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL9543318 | 0.83 | L3MBTL1 (0.42) | L3MBTL1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL1751139 | 0.83 | L3MBTL1 (0.71) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL9326166 | 0.82 | L3MBTL1 (0.44) | L3MBTL1 | |
| SCHEMBL9434878 | 0.82 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1 | |
| SCHEMBL23204604 | 0.82 | L3MBTL1 (0.48) | L3MBTL1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987253-A | Method for the synthesis of desferrioxamine B and analogs thereof | UNIVERSITY OF FLORIDA (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0347163-A2 | Method for the synthesis of desferrioxamine B and analogs thereof, and intermediates | THE UNIVERSITY OF FLORIDA (US) | 1989-12-20 | — | — | EP | disclosed |