SCHEMBL9543318

SCHEMBL9543318

N#CCCCCN(OCc1ccccc1)C(=O)CCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
CYP2C19 P33261 1/20 0.41
ALOX5 P09917 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HTT P42858 1/20 0.36
POLB P06746 1/20 0.36
GUSB P08236 1/20 0.36
MAOB P27338 1/20 0.36
KDM4A O75164 1/20 0.36
KDM5A P29375 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21023137 0.96 CYP3A4 (0.41) L3MBTL1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL9437255 0.89 EPOR (0.46) L3MBTL1TSHRKMT2AHTT
SCHEMBL9326820 0.88 L3MBTL1 (0.41) L3MBTL1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL9326758 0.88 L3MBTL1 (0.41) L3MBTL1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL9325011 0.87 L3MBTL1 (0.42) L3MBTL1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL9326166 0.86 L3MBTL1 (0.44) L3MBTL1MEN1KMT2A
SCHEMBL9326206 0.86 L3MBTL1 (0.42) L3MBTL1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL9327201 0.86 L3MBTL1 (0.42) L3MBTL1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL9326236 0.86 L3MBTL1 (0.44) L3MBTL1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL9775369 0.83 L3MBTL1 (0.47) L3MBTL1CYP3A4CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149046-B2 Antibacterial sideromycins Hsiri Therapeutics, Inc. (US) 2021-10-19 US disclosed
US-20190153010-A1 ANTIBACTERIAL SIDEROMYCINS Hsiri Therapeutics, LLC 2019-05-23 US disclosed
US-5254724-A Method for synthesis of desferrioxamine B, analogs and homologs thereof UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 1993-10-19 US disclosed
WO-1993016983-A1 COMPOUNDS USED IN CONTRAST PRODUCTS FOR RADIOGRAPHY GUERBET S.A. (FR) 1993-09-02 WO disclosed
WO-1993009088-A1 IMPROVED METHOD FOR SYNTHESIS OF DESFERRIOXAMINE B, ANALOGS AND HOMOLOGS THEREOF UNIVERSITY OF FLORIDA (US) 1993-05-13 WO disclosed
US-4987253-A Method for the synthesis of desferrioxamine B and analogs thereof UNIVERSITY OF FLORIDA (US) 1991-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11149046-B2 Antibacterial sideromycins SLC40A1, SFXN1, SLC39A14 L3MBTL1 1599/4885CYP3A4 3200/4885CYP2C9 3536/4885
US-20190153010-A1 ANTIBACTERIAL SIDEROMYCINS SLC40A1, SFXN1, SLC39A14 L3MBTL1 1599/4885CYP3A4 3200/4885CYP2C9 3536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.