SCHEMBL9775376

SCHEMBL9775376

BrCc1cccc2c(Br)csc12

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12281436 0.82 CYP2A6 (0.44) TBXAS1GABRA1GABRB2CYP2A6
SCHEMBL10689332 0.81 TBXAS1 (0.31) TBXAS1
SCHEMBL8583983 0.81 CYP1A2 (0.33) TBXAS1CYP2A6
SCHEMBL31662555 0.80 CYP2A6 (0.34) CYP2A6
SCHEMBL10689754 0.78 IFNAR1 (0.44) TBXAS1GABRA1GABRB2
SCHEMBL10759537 0.77 CYP17A1 (0.46) TBXAS1CYP2A6
SCHEMBL10689864 0.77 IDO1 (0.32)
SCHEMBL10693028 0.77 GPR35 (0.30)
SCHEMBL10692169 0.77 CYP2A6 (0.36) CYP2A6
SCHEMBL16237896 0.76 PSMB8 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068359-A Fungicides of benzothiophene and benzofuran compounds CIBA-GEIGY CORPORATION (US) 1991-11-26 US disclosed
EP-0404721-A2 Microbicides CIBA-GEIGY AG (CH) 1990-12-27 EP disclosed
US-4737516-A FUNGICIDES SANDOZ LTD. (CH) 1988-04-12 US disclosed