SCHEMBL9775405

SCHEMBL9775405

CC[Si](CC)(CC)c1ccccc1Br

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.34
BLM P54132 1/20 0.34
TAAR1 Q96RJ0 3/20 0.33
GRM2 Q14416 2/20 0.32
NOS3 P29474 2/20 0.32
NOS1 P29475 2/20 0.32
NOS2 P35228 2/20 0.32
PLCG1 P19174 1/20 0.31
IDO1 P14902 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
MAPK1 P28482 1/20 0.31
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7055834 0.82 TP53 (0.36) ALDH1A1TSHR
SCHEMBL988369 0.73 TSHR (0.43) ALDH1A1TSHRCYP1A2TAAR1
SCHEMBL6743956 0.73 ALDH1A1 (0.32) ALDH1A1TSHRCYP1A2CYP2D6NFKB1
SCHEMBL3761218 0.72 ALDH1A1 (0.43) ALDH1A1TSHRCYP1A2CYP2D6NFKB1
SCHEMBL31168893 0.72 ALDH1A1 (0.43) ALDH1A1TSHRCYP1A2CYP2D6NFKB1
SCHEMBL9775425 0.71 TSHR (0.41) ALDH1A1TSHRCYP1A2LMNATAAR1
SCHEMBL16537644 0.71 ALDH1A1 (0.41) ALDH1A1TSHRCYP2D6NFKB1HSD17B10
SCHEMBL21271563 0.71
SCHEMBL10419089 0.71 TAAR1 (0.32) TAAR1IDO1
SCHEMBL3669016 0.71 ALDH1A1 (0.34) ALDH1A1TSHRCYP1A2CYP2D6NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5027157-A Developing device provided with electrodes for inducing a traveling wave on the developing material MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
US-4971880-A MULTILAYER TONERS, DEVELOPERS, FOR ELECTROSTATIC LATENT IMAGES, CORES AND HALOGENATED CARBON PARTICLES MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1990-11-20 US disclosed
US-4867541-A FILM FORMED BY PLASMA POLYMERIZATION OF PHTHALOCYANINE COMPOUND MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
US-4828369-A ELECTROLYTES, PLASMA POLYMERIZATION OF HYDROCARBON, ALKALI METAL /COMPOUND/, ELECTRONEGATIVITY MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-05-09 US disclosed
US-4801515-A Photosensitive member having an overcoat layer MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-01-31 US disclosed
EP-0252442-A2 Photosensitive member having an overcoat layer Minolta Camera Kabushiki Kaisha (JP) 1988-01-13 EP disclosed