SCHEMBL9775425

SCHEMBL9775425

CC[Si](CC)(CC)c1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
LMNA P02545 1/20 0.41
PNMT P11086 1/20 0.39
IDO1 P14902 2/20 0.34
TAAR1 Q96RJ0 3/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD11B1 P28845 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
AOC3 Q16853 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP2A6 P11509 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7055834 0.82 TP53 (0.36) TSHRALDH1A1TP53HPGD
SCHEMBL9322666 0.76 LMNA (0.36) TSHRLMNAPNMTIDO1TAAR1
SCHEMBL988369 0.73 TSHR (0.43) TSHRTAAR1ALDH1A1NPC1RAB9A
SCHEMBL25413013 0.72 TSHR (0.47) TSHRLMNAPNMTIDO1ALDH1A1
SCHEMBL2565196 0.72 TSHR (0.47) TSHRLMNAPNMTIDO1TAAR1
SCHEMBL31193363 0.72 TSHR (0.47) TSHRLMNAPNMTIDO1TAAR1
SCHEMBL10419089 0.71 TAAR1 (0.32) IDO1TAAR1
SCHEMBL9775405 0.71 ALDH1A1 (0.39) TSHRLMNAIDO1TAAR1ALDH1A1
SCHEMBL21271563 0.71
SCHEMBL16537644 0.71 ALDH1A1 (0.41) TSHRLMNAALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5027157-A Developing device provided with electrodes for inducing a traveling wave on the developing material MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
US-4971880-A MULTILAYER TONERS, DEVELOPERS, FOR ELECTROSTATIC LATENT IMAGES, CORES AND HALOGENATED CARBON PARTICLES MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1990-11-20 US disclosed
US-4867541-A FILM FORMED BY PLASMA POLYMERIZATION OF PHTHALOCYANINE COMPOUND MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
US-4828369-A ELECTROLYTES, PLASMA POLYMERIZATION OF HYDROCARBON, ALKALI METAL /COMPOUND/, ELECTRONEGATIVITY MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-05-09 US disclosed
US-4801515-A Photosensitive member having an overcoat layer MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-01-31 US disclosed
EP-0252442-A2 Photosensitive member having an overcoat layer Minolta Camera Kabushiki Kaisha (JP) 1988-01-13 EP disclosed