SCHEMBL9775407

SCHEMBL9775407

NC(=O)c1c(-c2cc(Cl)ccc2O)cc(-c2cc(Cl)ccc2O)cc1-c1cc(Cl)ccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
SLC9A1 P19634 1/20 0.43
P2RX1 P51575 3/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PIM1 P11309 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
IKBKB O14920 1/20 0.39
CHUK O15111 1/20 0.39
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9775413 0.80 HPGD (0.42) MAPTHPGDALOX15MAPK1SMN1; SMN2
SCHEMBL9775390 0.77 ABL1 (0.43) CA1CA2P2RX1ALDH1A1HSD17B10
SCHEMBL552216 0.76 CA1 (0.67) CA1CA2P2RX1MAPTPKM
SCHEMBL29848306 0.76 CA1 (0.67) CA1CA2P2RX1MAPTPKM
SCHEMBL6242615 0.75 HSD17B10 (0.62) CA1CA2P2RX1MAPTALDH1A1
SCHEMBL31093991 0.75 HSD17B10 (0.62) CA1CA2P2RX1MAPTALDH1A1
Methane SCHEMBL28042257 0.73 HSD17B10 (0.59) CA1CA2P2RX1MAPTALDH1A1
SCHEMBL2408930 0.72 CA1 (0.56) CA1CA2P2RX1MAPTALDH1A1
SCHEMBL9441987 0.69 PIM1 (0.52) CA1CA2MAPTALDH1A1HSD17B10
SCHEMBL329155 0.69 BACE1 (0.62) CA1CA2MAPTALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0373690-A2 Flame-resistant polycarbonates containing units deriving from halogenated triphenolbenzamido compounds in their polymer chain ENICHEM S.p.A. (IT) 1990-06-20 EP claimed
US-5049644-A Self-extinguishing ENICHEM TECNORESINE S.P.A. (IT) 1991-09-17 US disclosed
EP-0373690-A2 Flame-resistant polycarbonates containing units deriving from halogenated triphenolbenzamido compounds in their polymer chain ENICHEM S.p.A. (IT) 1990-06-20 EP disclosed