Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775407 | 0.80 | CA1 (0.44) | HPGDALOX15IDO1KDM4EGAA | |
| SCHEMBL27991140 | 0.75 | ALOX15 (0.62) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL8743338 | 0.75 | ALOX15 (0.62) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL1175614 | 0.72 | HPGD (0.69) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL7058282 | 0.69 | BACE1 (0.62) | HPGDALOX15MCL1BCL2IDO1 | |
| SCHEMBL29408326 | 0.69 | BACE1 (0.62) | HPGDALOX15MCL1BCL2IDO1 | |
| SCHEMBL28195533 | 0.67 | CHUK (0.67) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL8490476 | 0.66 | ALOX15 (0.50) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL5690825 | 0.66 | IDO1 (0.47) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL22891490 | 0.66 | MAPT (0.62) | HPGDALOX15CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373690-A2 | Flame-resistant polycarbonates containing units deriving from halogenated triphenolbenzamido compounds in their polymer chain | ENICHEM S.p.A. (IT) | 1990-06-20 | — | — | EP | claimed |
| US-5049644-A | Self-extinguishing | ENICHEM TECNORESINE S.P.A. (IT) | 1991-09-17 | — | — | US | disclosed |
| EP-0373690-A2 | Flame-resistant polycarbonates containing units deriving from halogenated triphenolbenzamido compounds in their polymer chain | ENICHEM S.p.A. (IT) | 1990-06-20 | — | — | EP | disclosed |