Butadiene

Butadiene

SCHEMBL9775438

C=CC=C.Fc1ccc(F)c(F)c1F

nearest known ligand 0.42

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
ALDH1A1 P00352 2/20 0.33
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45430 0.82 CES2 (0.53) CES2CES1ALDH1A1CTSLCTSS
SCHEMBL29489580 0.82 CES2 (0.53) CES2CES1ALDH1A1CTSLCTSS
SCHEMBL3975406 0.78 CES2 (0.50) CES2CES1ALDH1A1CTSLCTSS
SCHEMBL11355080 0.78 CES2 (0.50) CES2CES1ALDH1A1CTSLCTSS
Ammonia Solution, Strong SCHEMBL3047305 0.78 CES2 (0.50) CES2CES1ALDH1A1CTSLCTSS
SCHEMBL285853 0.77 CES2 (0.36) CES2CES1ALDH1A1
SCHEMBL29620248 0.77 CES2 (0.36) CES2CES1ALDH1A1
SCHEMBL22418079 0.75 CES2 (0.31) CES2CES1
Hydrazine SCHEMBL3793747 0.74 CES2 (0.48) CES2CES1ALDH1A1
SCHEMBL16960497 0.73 CES2 (0.32) CES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4987209-A Diethynyl monomers and polymers thereof THE PRESIDENT AND FELLOWS OF HARVARD (US) 1991-01-22 US disclosed