Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.71 |
| ▸ | GAA | P10253 | 5/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775471 | 1.00 | MAPT (0.71) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL10937411 | 0.86 | MAPT (0.55) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL10937407 | 0.86 | MAPT (0.55) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL1702573 | 0.84 | MAPT (0.73) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL1702571 | 0.84 | MAPT (0.73) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL4668743 | 0.83 | MAPT (1.00) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL4668744 | 0.83 | MAPT (1.00) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL13777875 | 0.82 | MAPT (0.49) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL8181030 | 0.81 | MAPT (0.68) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL8181026 | 0.81 | MAPT (0.68) | MAPTGAAMAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990625-A | Process for synthesis of N,N-disubstituted hydrazone | CANON KABUSHIKI KAISHA (JP) | 1991-02-05 | — | — | US | disclosed |